When you need an antibiotic that fights common infections without the heavy side effects, Cefaclor, a second-generation cephalosporin antibiotic used to treat ear, lung, skin, and urinary tract infections. Also known as a broad-spectrum beta-lactam antibiotic, it's often chosen when penicillin doesn't work or isn't safe. But how does it really compare to the antibiotics you hear about every day—like amoxicillin, cephalexin, or azithromycin? It’s not just about which one works—it’s about which one works for you.
Cefaclor is a cephalosporin, a class of antibiotics that block bacterial cell wall formation, making them effective against many Gram-positive and some Gram-negative bacteria. That puts it in the same family as cephalexin and cefdinir, but it’s more resistant to certain enzymes that break down older antibiotics. Compared to amoxicillin, a penicillin-based antibiotic often used for ear infections and strep throat, Cefaclor works better against some resistant strains, especially in ear infections. But it’s not always stronger—just different. If you’ve had an allergic reaction to penicillin, Cefaclor might be a safer bet, though cross-reactivity can still happen. And unlike azithromycin, a macrolide antibiotic used for respiratory and skin infections, often taken in short bursts, Cefaclor usually requires dosing three times a day, which can be harder to stick with.
Side effects? Cefaclor can cause diarrhea, nausea, or rash—similar to many antibiotics. But it’s less likely than some to trigger severe gut issues like C. diff. It’s also cheaper than newer options like cefdinir, but not always as broad as ceftriaxone for serious infections. The real difference shows up in what doctors see: Cefaclor clears up ear infections in kids faster than amoxicillin in some cases, but it’s not the first choice for pneumonia. And if you’ve tried one antibiotic and it didn’t work, switching to Cefaclor might be the next logical step—not because it’s the best, but because it’s different enough to make a difference.
What you’ll find in the posts below isn’t just a list of drugs. It’s real comparisons—side by side—between Cefaclor and other antibiotics like Amoxil, Tetracycline, and more. You’ll see which ones work best for specific infections, which ones cost less, which ones cause fewer stomach issues, and when your doctor might reach for one over another. No fluff. No jargon. Just what you need to understand why one antibiotic gets prescribed over another—and what that means for your recovery.